This book is more for the general public (rather than physicists) and has the ambition to convince the readers to treat things more scientifically in all aspects of life. I don't really learn nearly as much from this book as compared to her last book "Warped Passges".
The book covers a lot of ground but I feel that the author has included too many topics including some that she may not really have expertise in, such as religion (Chap. 3 - 4) and risk management business (Chap. 11). The author can certainly discuss whatever she wants. But to me, she hasn't really said anything new or revolutionary in these two aspects. At the end of Chap. 3, she concludes that religion is simply not compatible with science and then just says things meekly without a strong emphasis (one way or another). When she discusses the collapse of our financial system in 2008, she seems to instill a doctrine or feeling that everything has been so obvious and if we had used our mind scientifically, the collapse would have been avoided. I'm totally unconvinced. Hindsight is 20/20.
I like that in the "Conclusion" chapter, she finally points out that technological breakthrough originates from basic scientific discovery/revolution and we should not just focus on short-term goals of technological advances and forfeit the long-term (and more uncertain) endeavor for basic scientific research.
She has made the point well that scientific theories may be applicable only in their relative scale; and to a large extent, it's probably too much an exaggeration to always emphasize things like "we don't understand quantum mechanics", considering that we have used quantum mechanics to make the most accurate theoretical prediction verified by experiments. The descriptions of LHC experiments just flew by me whereas I feel the most enriching when she explains and explores the possible fundamental discoveries in LHC such as supersymmetry, technicolor, extra dimension including the Kaluza-Klein particles and her "favorite" warped extra dimension theory (the graviton wavefunction decreases exponentially from the Gravitybrane to our Weakbrane --- thus solving the hierarchy problem), and even dark matter. Maybe I'm biased but I enjoy more when she discusses about the subjects in which she really has strong expertise.
A few places that look like typos/errors:
p. 72 (5th line) "travel a ways down" is probably "travel way down".
p. 286 (7th line), the endnote "58" should most likely be "60" (otherwise, "60" seems never used).
p. 314 (2nd line): In the sentence of "The idea is that as much that owing to ...", I think "as much that" shouldn't be there.
p. 359 (16th line): "It's role ..." should be "Its role ..." (without the apostrophe).